Thrombolytic Therapy in Acute Stroke

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Thrombolytic therapy of acute stroke.

Case 1. A 65-year-old right-handed man with no history of heart disease presented to the emergency department with right-sided weakness and an inability to speak. His wife last saw him well 1 hour before his arrival. His ECG showed atrial fibrillation with a ventricular response of 100 bpm; his blood pressure was 175/ 88 mm Hg. He was alert, but he did not produce or comprehend speech. He did n...

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Safety and feasibility of intravenous thrombolytic therapy in Iranian patients with acute ischemic stroke

  Background: Thrombolytic therapy is the only approved treatment for acute cerebral ischemia. The hemorrhagic transformation is the greatest complication of this treatment, which may occur after recanalization of occluded artery. The aim of this study was to determine factors associated with clinical improvement and worsening in patients with acute ischemic stroke treated with intravenous th...

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Intravenous thrombolytic therapy for acute ischemic stroke.

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Intravenous Thrombolytic Therapy for Acute Ischemic Stroke

n engl j med 364;22 nejm.org june 2, 2011 2138 This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented...

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Community-based thrombolytic therapy of acute ischemic stroke in Helsinki.

BACKGROUND AND PURPOSE Thrombolysis with alteplase is used in acute ischemic stroke within 3 hours after symptom onset in many stroke centers, but experience remains limited in Europe. METHODS Using eligibility and management criteria similar to those published by the American Heart Association, we treated 75 consecutive patients aged 21 to 83 years (mean age, 63.6 years; median Scandinavian ...

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ژورنال

عنوان ژورنال: International Journal of Gerontology

سال: 2008

ISSN: 1873-9598

DOI: 10.1016/s1873-9598(08)70054-1